What is Bufo?
Bufo alvarius, also known as Otac, is a toad that lives in Northern Mexico. The toad produces a milky secretion that contains 5-MeO-DMT, a tryptamine that is naturally occurring in the human brain and is known as the "God Molecule."
Bufo comes from the Seri, an indigenous group in the Sonoran Desert. The use of 5-MeO-DMT can be traced back thousands of years from different plant and animal sources that many cultures used as a direct connection to God.
THE MEDICINE
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During a ceremony, the secretion from the toad is vaporized and inhaled. Your experience can last from ten minutes to over an hour, depending on dosage and retention.
While the approach to each person is individual, the first dose is usually a lower "Harmony Dose" to allow you to enter into the vibration of the medicine, which then may be followed by a higher dose.
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After applying the spirit medicine, your consciousness may leave your body as you enter the space of "everything and nothing." On the ground, encompassed in a protected space of love, energies not in resonance with this high vibration may leave your body. The experience brings upon the remembrance of your true essence and connection to the divine. The illusion of separation dissolves as you reenter the infinite space of unity and love.
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Our mind is COHERENT WITH THE WORLD, and when we do not repress the INTUITIONS that link us with other people and with nature, we can become aware of our ONENESS WITH THE UNIVERSE.
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- James Oroc, The Tryptamine Palace: 5-MeO-DMT and the Sonoran Desert Toad
god molecule
The Sonoran Desert Toad (Incilius alvarius) is being exploited for something it produces from its skin: 5-MeO-DMT. It produces this so-called “god molecule” in a potent, easily accessible concentration, and is thus far the only known vertebrate to do so. When inhaled, this molecule can completely overwhelm the senses, sending one out of consensus reality — inducing significant feelings of existential illumination and meaning; love; interconnectedness; the extreme diminishment of one's ego; and the alleviation of certain psychiatric problems. Others take this extreme substance recreationally. However, instances of terror-induced trauma, and death are also associated with misuse of this substance, which is not yet fully appreciated by most scientists and health professionals.
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The late enthusiast of 5-MeO-DMT, James Oroc, opined that the modern reference to psychedelics as “medicine” in the “psychedelic renaissance” is warped from ancient context – reflecting existential crises and imperialism of the Global North, where psychedelic and spiritual experiences have been repressed or abused (Moore, 2018). Despite reports of harm from the malpractice of 5-MeO-DMT, ongoing studies assessing the nature of its use in more controlled settings have shown that it may hold important therapeutic potential. Using synthetic 5-MeO-DMT, eighty percent of survey respondents from one observational study reported improvements in symptoms of depression and anxiety (Davis, So, Lancelotta, Barsuglia, & Griffiths, 2019). Scientific reporting on the beneficial effects of toad-sourced 5-meo-DMT (Uthaug et al., 2019) must be careful to avoid misguiding support for its extraction from toads (Uthaug, 2019). There have been no large-scale clinical studies of 5-MeO-DMT. This should change as various pharmaceutical projects are intent on making 5-MeO-DMT a more widely approved substance (e.g. GHRes.com). Additionally, Beckley Psytech (Oxford, England) raised $80 million through eager investors to initiate studies leading to trials of proprietarily-synthesized 5-MeO-DMT for treatment-resistant depression (Business Wire, 2021).